TOP 5 Anti-Aging Supplements: Harnessing the Power of Nature
Oppdatert 2025-11-11
Biological age is based on the cellular age of one's health, and the essence of anti-aging is to reduce biological age. Longevity experts have summarized five supplements suitable for combating aging, some of which can be obtained through food as well.
Urolithin A Anti-Aging Supplements
01
Urolithin A Anti-Aging Supplements
Urolithin A is a natural metabolite with antioxidant and anti-proliferative properties. Nutritionists at Southeast University in the United States have found that using urolithin A as a dietary intervention can delay the aging process and prevent the development of age-related diseases. Urolithin A promotes mitochondrial autophagy, helping to recycle damaged mitochondria and maintain cell vitality. Although urolithin A is not directly obtained from the diet, compounds such as ellagic acid and ellagitannins found in nuts, pomegranates, grapes, and other berries are metabolized by intestinal microbes to produce urolithin A.
02
Research published in the journal "Aging and Disease" by clinical molecular biologists at the University of Oslo in Norway shows that the consumption of nicotinamide adenine dinucleotide (NAD+) is associated with aging and serves as the basis for various age-related diseases such as metabolic disorders, cancer, and neurodegenerative diseases. NMN is a bioactive nucleotide that can elevate NAD+ levels. It is worth noting that due to ongoing investigations by pharmaceutical companies, the FDA recently decided that NMN cannot be sold in the United States as a dietary supplement. In contrast, nicotinamide riboside (NR), a derivative of vitamin B3, is a similar functional nutritional supplement available in the United States. NMN is naturally present in the body but decreases with age. Some fruits and vegetables rich in NMN include avocados, broccoli, cabbage, edamame, and cucumbers.
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Spermidine Anti-Aging Supplements
Spermidine is a naturally occurring polyamine that has garnered attention in recent years for its potential to prolong lifespan and increase healthy lifespan. Researchers at Kyoto Prefectural University of Medicine in Japan published a study in "Scientific Reports" showing that normal aging processes decrease the concentration of endogenous spermidine in the body. However, this phenomenon was not observed in centenarians, who had relatively high concentrations of spermidine in their bodies. Spermidine promotes autophagy. Foods with high spermidine content include whole grains, seaweed, shiitake mushrooms, nuts, bracken, and purslane.
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Fisetin Anti-Aging Supplements
Senescent cells are cells that deteriorate with age and release inflammatory molecules into surrounding tissues. Fisetin significantly affects the aging process by reducing the accumulation of these dysfunctional cells and improving overall health. Geneticists at Tianjin Medical University found that fisetin can reverse premature aging signs in telomerase-deficient mice. Fisetin is found in various fruits (strawberries, apples, mangoes, persimmons, kiwis, and grapes), vegetables (tomatoes, onions, cucumbers), nuts, and wine.
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Curcumin Anti-Aging Supplements
Curcumin is an active compound found in turmeric with anti-inflammatory and antioxidant properties. Experimental biologists at the Polish Academy of Sciences found that curcumin can reduce aging symptoms and delay the progression of age-related diseases directly involving senescent cells, thereby extending lifespan. In addition to turmeric, foods high in curcumin content include ginger, garlic, onions, black pepper, mustard, and curry.
While these supplements have the potential to prolong lifespan, it's advisable to consult a doctor before taking them.
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